Efudix [5-fluorouracil cream]
5fu (unlicensed) - "chemotherapy" Salk RS et al. Topical 5% 5-Fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study. J Drugs in Dermatology 2006; 5(5): 317-23
161 patients screened
20 5fu under tape occlusion
19/20 =95% resolved within 12 weeks
Ave time to cure 9 weeks
3/20 recurrence at 6 mo
Safe efficacious - mild to moderate ulceration with mild maceration & erythema
Ave no of warts - 2.9
5fu bd 12 w |