It might just be easier to send man to the moon than to treat or cure warts.

But here are some strategies

1. Do nothing
2. Salicylic acid
3. Cryotherapy every 2-3 weeks until clearance ( six treatments maximum)
4. Curettage and cautery
5. Aldara - imiquimod - off licence
6. Duct tape
7. Ablative laser
8. Efudix [5-fluorouracil cream]
5fu (unlicensed) - "chemotherapy" Salk RS et al. Topical 5% 5-Fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study. J Drugs in Dermatology 2006; 5(5): 317-23

161 patients screened
20 5fu under tape occlusion
19/20 =95% resolved within 12 weeks
Ave time to cure 9 weeks
3/20 recurrence at 6 mo
Safe efficacious - mild to moderate ulceration with mild maceration & erythema
Ave no of warts - 2.9
5fu bd 12 w

Check out the Cochrane review on warts- the evidence for one wart treatment being better than another.

2014 guidelines


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